&ldq o;An excellent compendium of all things CRISPR from some of the leading minds in the field. With thorough coverage from every angle and beautifully detailed illustrations, this book is not to be missed!” b>Jennifer A. Doudna,
Professor of Chemistry, Biochemistry& Molecular Biology, UC Berkeley; Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of CRISPR technology “” < >David R. Liu,
Director of the Merkin Institute at the Broad Institute of MIT and Harvard; Professor of Chemistry and Chemical Biology at Harvard University; coinventor of base editing and prime editing“A must read! The CRISPR topics, written by world-leading experts, span from the fascinating mechanistic underpinnings to the ingenious applications. One can read from start to finish or pick and choose themes. Either way, the book delivers utterly enjoyable learning!” < >Bonnie Bassler,
Squibb Professor and Chair, Princeton University Department of Molecular Biology; Howard Hughes Medical Institute InvestigatorCRISPR-Cas systems have revolutionized the science of gene editing and their possible applications continue to expand, from basic research to potentially groundbreaking medical and commercial uses. Led by a distinguished team of editors,CRISPR: Biology and Applications explores the subject matter needed to delve into this fascinating area. Topics covered include: - Classific tion and molecular mechanisms of CRISPR-Cas systems
- CRISPR-Cas evolution, regulation, expression, and function
- Uses for gene editing and modulation of gene expression
- CRISPR-bas d antimicrobials and phage resistance for medical and industrial purposes
Written by internationally renowned authors,CRISPR: Biology and Applications serves as both an introductory guide for those new to the field and an authoritative reference for seasoned researchers whose work touches this evolving and headline- making science.
ABOUT THE EDITORS Rodolphe Barrangou is the Todd R. Klaenhammer Distinguished Professor in the Department of Food, Bioprocessing and Nutrition Sciences at North Carolina State University; a member of the AAM, NAS, NAE, and NAI; a cofounder of Intellia Therapeutics, Locus Biosciences, Ancilia Biosciences, CRISPR Biotechnologies, and TreeCo; and Editor- in-Chief ofThe CRISPR Journal. Erik J. Sontheimer is the Pillar Chair in Biomedical Research and Professor in the RNA Therapeutics Institute at the University of Massachusetts Chan Medical School; an Associate Editor ofRNA; a member of the AAM; a cofounder of Intellia Therapeutics; and a Scientific Advisory Board member at Tessera Therapeutics. Luciano A. Marraffini is the Kayden Family Professor and Head of the Laboratory of Bacteriology at The Rockefeller University; a Howard Hughes Medical Institute Investigator; a member of the AAM, AAAS, and NAS; and a cofounder of Intellia Therapeutics, CRISPR Biotechnologies, and Eligo Biosciences. |
