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In Vivo Models of Inflammation Volume 2

:	Christopher S. Stevenson, Lisa A. Marshall, Douglas W. Morgan
:	Christopher S. Stevenson, Lisa A. Marshall, Douglas W. Morgan
:	In Vivo Models of Inflammation Volume 2
:	Birkhäuser Basel
:	9783764377601
:	2
:	CHF 133.60
:

:	Nichtklinische Fächer
:	English

:	203
:	Wasserzeichen/DRM
:	PC/MAC/eReader/Tablet
:	PDF

In Vivo Models of Inflammation (Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first, describing and updating the standard models that are most utilized for specific disease areas. New models are included exploring emerging areas of inflammation research.

	Contents	5
	List of contributors	6
	Preface to the first edition	8
	Preface to the second edition	9
	Introduction	10
	Asthma	10
	Mouse models	11
	Guinea pig models	17
	Rat models	18
	Rabbit models	21
	Canine models	21
	Sheep models	22
	Primate models	23
	References	26
	Introduction	38
	Chronic obstructive pulmonary disease	38
	In vivo modeling systems for chronic obstructive pulmonary disease	38
	Elastase-induced lung inflammation and emphysema	41
	Cigarette smoke-induced inflammation and lung destruction	46
	Future directions	55
	Conclusion	56
	References	57
	Introduction	67
	Murine models of allergen-induced airway hyperresponsiveness and inflammation	67
	Murine models of allergen-induced AHR and inflammation: functional assessments	69
	Significance of murine models	76
	References	85
	Introduction	92
	Skin inflammatory disorders	92
	Atopic dermatitis models	94
	Psoriasis models	105
	Summary	118
	References	120
	Introduction	128
	In vivo models of neurogenic inflammation	128
	Neurogenic arterial vasodilatation and plasma extravasation	131
	Mucus secretion	134
	Motor effects in the airways and urinary tract	136
	References	137
	Introduction	143
	Animal models of inflammatory bowel disease	143
	Spontaneous or natural models	147
	Immunological, bacterial and bacterial byproduct model	153
	Animal models of physical injury	155
	Genetically engineered models	161
	Adoptive transfer models	167
	Concluding remarks	168
	References	168
	Introduction	181
	Preclinical models of vascular inflammation	181
	Models of vascular inflammation	184
	Conclusions	194
	References	194
	Index	204
	The PIR-Series Progress in Inflammation Research	209