: Yves Christen, Bruce M. Spiegelman, Karine Clément
: Karine Clément, Bruce M. Spiegelman
: Novel Insights into Adipose Cell Functions
: Springer-Verlag
: 9783642135170
: 1
: CHF 189.80
:
: Nichtklinische Fächer
: English
: 147
: Wasserzeichen/DRM
: PC/MAC/eReader/Tablet
: PDF
Obesity is a disease of society and economic transition spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual's health will be negatively affected. Overweight is thus being considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders.This volume provides the most up to date insights into the biology of a complex endocrine organ: the adipose tissue.
Foreword6
Contents8
Contributors10
Pathological Alteration of Human Adipose Tissue in Obesity14
1 Natural History of Human Obesity14
2 Human White Tissue in Obesity: Inflammation, Metabolic Dysfunction and Fibrosis15
3 Adipose Cell Plasticity17
4 Multiple Inflammatory Cells Involved18
5 Perturbed Phenotypes of Preadipocytes and Adipocytes by Inflammation19
6 Importance of the Extracellular Matrix20
7 Specific Roles of Chemokines in Human Adipose Tissue: Example of Rantes/CCL520
8 Somatic Consequences of Inflammation: Visceral Adipose Tissue, Fatty Acids, Adipokines and Lipokines as the Guilty Players21
9 Conclusion22
References23
Dynamics of Human Adipose Tissue. Regulatory