| Foreword | 8 |
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| Preface | 10 |
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| Acknowledgment | 14 |
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| Contents | 15 |
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| Contributors | 17 |
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| 1 Cardiovascular Disease in Racial/Ethnic Minorities: Overview and Perspectives | 19 |
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| 1. Introduction | 20 |
| 2. Current Concepts of Race and Ethnicity: Facts and Fallacies | 21 |
| 3. Overview of CVD in Racial/Ethnic Minorities Chapters | 23 |
| 3.1 Epidemiology of Cardiovascular Diseases and Risk Factors Among Racial and Ethnic Populations in the United States | 23 |
| 3.2 Unmasking Racial/Ethnic Disparities in Cardiovascular Disease: Nutritional, Socioeconomic, Cultural and Healthcare-Related Contributions | 23 |
| 3.3 Race and Genetics | 24 |
| 3.4 Race, Genetics, and Cardiovascular Disease | 25 |
| 3.5 Hypertension and Stroke in Racial/Ethnic Groups | 26 |
| 3.6 Dyslipidemia in Racial and Ethnic Groups | 26 |
| 3.7 Novel and Emerging Risk Factors in Racial/Ethnic Groups | 27 |
| 3.8 Therapeutic Lifestyle Interventions in a Multicultural Society | 28 |
| 3.9 Obesity and the Cardiometabolic Syndrome: Impact on Chronic Kidney Disease and CVD | 28 |
| 3.10 Risk Calculation and Clustering within Racial/Ethnic Groups | 29 |
| 3.11 Cardiovascular Imaging in Racial/Ethnic Populations: Implications for the Adequate Application of Cardiovascular Imaging Techniques Guided by Racial and Ethnic Risk | 29 |
| 3.12 Unique Aspects of Vascular and Cardiac Ultrasound in Racial/Ethnic Groups | 30 |
| 3.13 Heart Failure in Racial/Ethnic Populations | 31 |
| 3.14 Minority Women and CVD | 32 |
| 4. Perspectives on CV Morbidity/Mortality in Racial/Ethnic Minorities | 32 |
| 5. Practical Approaches to Eliminating Disparities | 33 |
| 6. Socioeconomic-Disadvantaged Status and CVD | 35 |
| 7 Future Considerations | 35 |
| 2 Epidemiology of Cardiovascular Diseases and Risk Factors Among Racial/Ethnic Populationsin the United States | 40 |
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| 1 Summary | 40 |
| 2 Introduction | 41 |
| 3 Strengths and Limitations of the Existing Epidemiologic Data | 42 |
| 4 Life Expectancy and Summary Measures ofPopulation Health | 43 |
| 5 Cardiovascular Risk Factors and Biomarkers | 45 |
| 5.1 Self-Reported Behavioral and Lifestyle Risks | 48 |
| 5.2 Prevalence and Trends in Measured Risk Factors | 48 |
| 5.3 Emerging Risk Factors and Biomarkers of Cardiovascular Risk | 53 |
| 5.4 Markers of Subclinical Cardiovascular Disease | 54 |
| 6 Cardiovascular Morbidity | 57 |
| 7 Access to Care and the Quality ofHealth CareDelivered | 58 |
| 8 Progress Made in the Elimination ofHealth Disparities | 59 |
| 9 Summary and Conclusions | 61 |
| 3 Unmasking Racial/Ethnic Disparities inCardiovascular Disease: Nutritional, Socioeconomic, Cultural, and Health-Care-Related Contributions | 68 |
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| 1 Population-Based CVD Burden/Racial and Ethnic Disparities in CVD | 69 |
| 2 Likely Causes of Population-Based Differences in CVD Burden by Race/Ethnicity | 71 |
| 2.1 The Role of Genetics in Race/Ethnicity Disparities in CVD | 72 |
| 2.2 Environmental Effects | 73 |
| 2.3 Low Birth Weight | 76 |
| 2.4 Dietary Nutrients and Physiologic Effects upon CVD | 77 |
| 2.5 Dietary Nutrients, Socioeconomic Status, and Race | 78 |
| 2.6 Physical Inactivity | 79 |
| 2.7 Geography and Acculturation | 79 |
| 3 Socioeconomic Status and Cardiovascular Disease | 80 |
| 4 Cardiovascular Disease Disparities in Health-Care Settings | 81 |
| 4.1 Coronary Ischemia and Myocardial Infarction | 82 |
| 4.2 Hypertension, Hyperlipidemia, and Other Cardiovascular Risk Factors | 82 |
| 4.3 Congestive Heart Failure | 82 |
| 4.4 Health System and Provider Characteristics Linked to CVD Disparities | 83 |
| 4.5 Proposed Solutions for Reducing/Eliminating CVD Health Disparities in Health-Care Settings | 83 |
| 5 Cultural Competency and CVD Health Care | 85 |
| 5.1 Health-Care Quality and the Underserved | 85 |
| 5.2 Cultural Competency Defined | 85 |
| 5.3 Cardiovascular Disease and Etiology | 87 |
| 5.4 Laizze Faire or Fatalistic Attitudes | 87 |
| 3.1 Summary | 88 |
| 4 Race and Genetics | 97 |
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| 1 Introduction | 98 |
| 2 How is Genetic Variation Structured? | 99 |
| 3 Measure and use of Genetic Ancestry | 101 |
| 4 Finding Disease Susceptibility Genes in Admixed Populations | 103 |
| 5 Has Natural Selection Shaped Genetic Variation? | 103 |
| 6 Conclusion | 104 |
| 5 Race, Genetics and Cardiovascular Disease | 108 |
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| 1 Introduction | 109 |
| 2 Predisposition | 110 |
| 3 Screening | 111 |
| 4 Pathophysiology | 112 |
| 4.1 Healt
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