: Helena M. Tabery
: Herpes Simplex Virus Epithelial Keratitis In Vivo Morphology in the Human Cornea
: Springer-Verlag
: 9783642010125
: 1
: CHF 47.50
:
: Klinische Fächer
: English
: 58
: Wasserzeichen
: PC/MAC/eReader/Tablet
: PDF
As a young ophthalmologist, I found corneal epithelial diseases a subject diffcult to grasp. One day, it occurred to me that the reason might be a lack of images showing the nature of the components of the changes visible with the slit lamp. With the slit lamp, the inevitable eye movements that blur the image limited the magnifcation level, but perhaps photography might be the answer. It was not a short journey, but in the end the idea proved right. By trial and error, the quality of the images improved, and after some time, I found that the resolution allowed reasonable comparisons with available images of histological preparations. Such comparisons allowed better und- standing of the substructures of epithelial in vivo lesions and, in conjunction with their in vivo dynamic features, eventually an understanding of at least some mechanisms behind them. This book, originating from over 20 years of experience with observations of ocular surface changes at high magnifcation level, covers several aspects of corneal epithelial lesions caused in humans by herpes simplex virus: various shapes of the lesions, their substructure and mechanisms behind them; morphological features of the healing p- cess, sequelae, complications, and some accompanying signs; and some rare cases. For those less familiar with the slit lamp image, I have added explanatory drawings to facilitate comprehension.

Herpes Simplex Virus Epithelial Keratitis1
The Morphology of Herpes Simplex Virus Epithelial Keratitis10
Anchor 310
HSV Cytopathic Effect: Early Changes11
Comment12
HSV Cytopathic Effect: Advanced Changes13
Comment14
Early HSV In Vivo Lesions: Surface Elevation and Disruption15
An Advanced HSV In Vivo Lesion: Loss of Substance16
HSV Lesions: Surface Elevation, Depression, and Fluid Diffusion17
HSV Lesions: Epithelial and Stromal Fluid Diffusion18
Optical Section Through the Cornea18
Rose Bengal Dye Staining of HSV Lesions19
Comment20
An HSV Dendritic Figure21
Comment22
An HSV Dendritic Figure (Continued)23
The Origin of HSV Dendritic Figures25
Various Shapes of HSV Dendritic Figures26
Some Other Shapes of HSV Lesions27
Comment27
Comment27
Precursors of HSV Geographic Lesions29
HSV Geographic Lesions30
Comment30
A Case of Primary HSV Keratitis31
Case Report31
Addendum: HSV Conjunctival Lesions32
Comment32
Healing of Herpes Simplex Virus Epithelial Keratitis Treated with Acyclovir Ointment and Short-Term Sequelae of the Infection33
Anchor 333
Healing of HSV Epithelial Keratitis with Acyclovir Ointment34
Case Report35
Healing of HSV Epithelial Keratitis with Acyclovir Ointment36
Healing of HSV Epithelial Keratitis with Acyclovir Ointment37
Case Report37
Healing of HSV Epithelial Keratitis with Acyclovir Ointment38
Healing of HSV Epithelial Keratitis with Acyclovir Ointment40
Case Report40
Healing of HSV Epithelial Keratitis with Acyclovir Ointment: A Treatment Failure41
Case Report41
Side Effects of Acyclovir Ointment42
Comment42
Complications, Accompanying Signs, Recurrences, and Long-Term Sequelae of Herpes Simplex Virus Epithelial Keratitis43
Anchor 343
Case 1. HSV Epithelial Keratitis: A Fresh and an Older Lesion44
Case Report44
Comment45
Healing Followed by Epithelial Breakdown and a New Repair (Case 1, cont.)46
Case 2. Healing of HSV Epithelial Keratitis, Accompanying Signs, and Sequelae48
Case ReportA 72-year-old woman with severe visual impairment in her right eye (caused by macular degeneration) presented with 48
Healing of HSV Epithelial Keratitis, Accompanying Signs, and Sequelae (Case 2, cont.)52
Healing of HSV Epithelial Keratitis, Accompanying Signs, and Sequelae (Case 2, cont.)54
Healing of HSV Epithelial Keratitis, Accompanying Signs, and Sequelae (Case 2, cont.)56
Addendum56
Case 3. HSV Epithelial Keratitis and Stromal Infiltrates57
Case Report57
Case 4. HSV Epithelial Keratitis Preceded by Anterior Uveitis and Disciform Keratitis58
Case Report58
Addendum58
HSV Epithelial Keratitis and Dry Eye (Case 4, cont.)59
Case 5. Recurrent HSV Epithelial Keratitis in a Patient with Dry Eye60
Case Report60
Bibliography62
Index63