: M. Lader, S. R. Pandi-Perumal, D. P. Cardinali
: Malcolm H Lader, Daniel P. Cardinali, S. R. Pandi-Perumal
: Sleep and Sleep Disorders: A Neuropsychopharmacological Approach
: Springer-Verlag
: 9780387276823
: 1
: CHF 189.50
:
: Pharmazie
: English
: 309
: Wasserzeichen
: PC/MAC/eReader/Tablet
: PDF

Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives.  This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

CONTENTS5
EDITORS7
CONTRIBUTORS7
FOREWORD12
PREFACE13
Section I: Basic Pharmacology14
GABAa Receptor Subtypes in Sedation and Hypnosis15
Sleep Hippocampal Theta Rhythm and sensory Processing22
Monoamitiergic Mechanisms in the Regulation of Sleep- Wakefulness: Special Emphasis on Preoptic Noradrenergic System27
REM Sleep Function and Brain Monoamine Regulation: An Application of the Search Activity Concept39
Role of Wakefulness Area in the Brainstem Reticular Formation in Regulating Rapid Eye Movement Sleep48
The Mechanistic Relationship between NREM Sleep and Anesthesia55
Section II: Chronopharmacology65
Time- Dependent Psychotropic Drug Effects: Hints of Pharmacochronomics, Broader than Circadian Time Structures66
Melatonin Interaction with BZ- GabaA Receptors: Implications for Sleep Induction107
Melatonin: A Chronobiotic that Not Only Shifts Rhythms112
Melatonin and Human Sleep119
Melatonin Efficacy to Treat Circadian Alterations of Sleep in Alzheimer's Disease123
Pharmacotherapy for Seasonal Affective Disorder133
Use and Discontinuation of Hypnosedative Medications139
Section III: Clinical Pharmacology145
Long- Term Use of Sleeping PiUs in Chronic Insomnia146
Risks of Chronic Hypnotic Use152
Meets of Psychotropics on Driving Performance157
Diagnosis, Pathophysiology and Treatment of Hypersomnias162
Chronic Disease and Sleep Architecture: Pharmacotherapeutic Considerations174
Benzodiazepines for Sedation in Infants and Children181
The Pharmacological Management of Fatigue and Sleepiness in Affective Disorders194
Next- Day Residual EflFects of Sleeping Medications on Driving Ability: A Review of the Literature199
Sleep and Pain212
Head Injuries and Sleep221
Psvchopharmacological Management of Restless Legs syndrome and Periodic Limb Movements in Sleep227
A Comparison of Visual Analog Scale and Categorical Ratings in Assessing the Patient's Estimate of Sleep Quality231
The Pharmacostrateey of Treating Sleep Disorders in Parkinsonism236
The Neuropharmacology of Nightmares252
The Night Eating Syndrome262
Drug Effects on Dreaming267
Sleep Problems in Primary Care273
SSRIs and Sleep in Man280
Sleep and Antipsychotic Drugs in Schizophrenia Patients285
Sleep and Epilepsy: From Interrelationships to Influence of Antiepileptic Drugs293
Herbal Medicines and Sleep308
INDEX315