: Jayna L. Ditty, Shannon R. Mackey, Carl H. Johnson
: Jayna Ditty, Shannon R. Mackey, Carl H. Johnson
: Bacterial Circadian Programs
: Springer-Verlag
: 9783540884316
: 1
: CHF 132.70
:
: Mikrobiologie
: English
: 333
: Wasserzeichen/DRM
: PC/MAC/eReader/Tablet
: PDF

Since the discovery of circadian rhythms in cyanobacteria in the late 1980s, the field has exploded with new information. The cyanobacterial model system for studying circadian rhythms, 'Synechococcus elongatus', has allowed a detailed genetic dissection of the bacterial clock due to the methods currently available in molecular, structural, and evolutionary biology.

This book addresses multiple aspects of bacterial circadian programs: the history and background of the cyanobacteria and circadian rhythms in microorganisms, the molecular basis, structure, and evolution of the circadian clock, entrainment of the oscillator with the environment and the control of downstream processes by the clock, the demonstration of adaptive significance and the prokaryotic clock's remarkable stability, and mathematical and synthetic oscillator models for clock function.

Experts in the field provide a timely and comprehensive review and a stepping-stone for future work on this amazing group of microorganisms and timing.

Preface5
Contents7
Contributors9
Classic Circadian Characteristics: Historical Perspective and Properties Relative to the Synechococcus elongatus PCC 7942 Model12
Speculation and Hoopla: Is Diversity Expected in Cyanobacterial Circadian Timing Systems?29
Circadian Rhythm of Cyanothece RF-1 (Synechococcus RF-1)48
The Decade of Discovery: How Synechococcus elongatus Became a Model Circadian System 1990–200071
The Kai Oscillator95
NMR Studies of a Timekeeping System110
Structural Aspects of the Cyanobacterial KaiABC Circadian Clock128
Mechanisms for Entraining the Cyanobacterial Circadian Clock System with the Environment148
Factors Involved in Transcriptional Output from the Kai- Protein- Based Circadian Oscillator164
Chromosome Compaction: Output and Phase176
Cell Division Cycles and Circadian Rhythms190
The Adaptive Value of the Circadian Clock System in Cyanobacteria212
Stability and Noise in the Cyanobacterial Circadian Clock229
The Circadian Clock Gear in Cyanobacteria: Assembled by Evolution246
Circadian Clocks of Synechocystis sp. Strain PCC 6803, Thermosynechococcus elongatus, Prochlorococcus spp., Trichodesmium spp. and Other Species264
Mathematical Modeling of the In Vitro Cyanobacterial Circadian Oscillator288
A Synthetic Biology Approach to Understanding Biological Oscillations: Developing a Genetic Oscillator for Escherichia coli306
Index335