| Preface | 6 |
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| Contents | 7 |
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| Contributors | 12 |
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| STEM CELLS | 20 |
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| STEM CELLS INTO LIVER - BASIC RESEARCH AND POTENTIAL CLINICAL APPLICATIONS | 21 |
| MESENCHYMAL STEM CELLS INCREASE SELF-RENEWAL OF SMALL INTESTINAL EPITHELIUM AND ACCELERATE STRUCTURAL RECOVERY AFTER RADIATION INJURY | 36 |
| OPTIMIZING VIRAL AND NON-VIRAL GENE TRANSFER METHODS FOR GENETIC MODIFICATION OF PORCINE MESENCHYMAL STEM CELLS | 48 |
| TRANSPLANTATION OF BONE MARROW STROMAL CELLS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | 66 |
| SOLUBLE AND INSOLUBLE SIGNALS | 82 |
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| CHONDROCYTE SIGNALING AND ARTIFICIAL MATRICES FOR ARTICULAR CARTILAGE ENGINEERING | 83 |
| OSTEOINDUCTION WITH COLLOSS®, COLLOSS® E, AND GFm | 103 |
| BIGLYCAN IS A POSITIVE MODULATOR OF BMP-2 INDUCED OSTEOBLAST DIFFERENTIATION | 117 |
| USE OF NEOPTERIN AS A BONE MARROW HEMATOPOIETIC AND STROMAL CELL GROWTH FACTOR IN TISSUE-ENGINEERED DEVICES | 130 |
| SCAFFOLDS AND MATRIX DESIGN | 137 |
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| INJECTABLE SYNTHETIC EXTRACELLULAR MATRICES FOR TISSUE ENGINEERING AND REPAIR | 138 |
| TEMPORAL CHANGES IN PEG HYDROGEL STRUCTURE INFLUENCE HUMAN MESENCHYMAL STEM CELL PROLIFERATION AND MATRIX MINERALIZATION | 147 |
| NOVEL BIOPHYSICAL TECHNIQUES FOR INVESTIGATING LONG-TERM CELL ADHESION DYNAMICS ON BIOMATERIAL SURFACES | 162 |
| EVALUATION OF VARIOUS TYPES OF SCAFFOLD FOR TISSUE ENGINEERED INTERVERTEBRAL DISC | 177 |
| PHYSICOCHEMICAL CHARACTERIZATION OF PHOTOPOLYMERIZABLE PLGA BLENDS | 192 |
| POROUS TANTALUM TRABECULAR METAL SCAFFOLDS IN COMBINATION WITH A NOVEL MARROW PROCESSING TECHNIQUE TO REPLACE AUTOGRAFT | 206 |
| PREPARATION OF SPONGE USING PORCINE SMALL INTESINAL SUBMUCOSA AND THEIR APPLICATIONS AS A SCAFFOLD AND A WOUND DRESSING | 218 |
| BIOREACTOR AND ASSESSMENT TECHNOLOGIES | 232 |
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| MODULATION OF CELL DIFFERENTIATION IN BONE TISSUE ENGINEERING CONSTRUCTS CULTURED IN A BIOREACTOR | 233 |
| BIOREACTORS FOR TISSUES OF THE MUSCULOSKELETAL SYSTEM | 250 |
| NON-INVASIVE MONITORING OF TISSUE-ENGINEERED PANCREATIC CONSTRUCTS BY NMR TECHNIQUES | 267 |
| ANIMAL MODELS AND CLINICAL STRATEGIES | 283 |
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| FROM MOLECULES TO MATRIX: CONSTRUCTION AND EVALUATION OF MOLECULARLY DEFINED BIOSCAFFOLDS | 284 |
| AGE-RELATED DIFFERENCES IN ARTICULAR CARTILAGE WOUND HEALING: A POTENTIAL ROLE FOR TRANSFORMING GROWTH FACTOR ß1 IN ADULT CARTILAGE REPAIR | 301 |
| INTRINSIC VERSUS EXTRINSIC VASCULARIZATION IN TISSUE ENGINEERING | 314 |
| PREDICTIVE VALUE OF IN VITRO AND IN VIVO ASSAYS IN BONE AND CARTILAGE REPAIR WHAT DO THEY REALLY TELL US ABOUT THE CLINICAL PERFORMANCE? | 330 |
| SCIENCE, REGULATION, AND THE PUBLIC | 364 |
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| ENGINEERED TISSUES: THE REGULATORY PATH FROM CONCEPT TO MARKET | 365 |
| TISSUE ENGINEERING STRATEGIES | 379 |
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| FIBRIN IN TISSUE ENGINEERING | 380 |
| ECTOPIC BONE INDUCTION BY EQUINE BONE PROTEIN EXTRACT | 394 |
| ADIPOSE TISSUE INDUCTION IN VIVO | 404 |
| OCULAR TISSUE ENGINEERING | 414 |
| MOLECULAR MECHANISM OF OSTEOCHONDROPROGENITOR FATE DETERMINATION DURING BONE FORMATION | 431 |
| Author Index | 442 |
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| Subject Index | 444 |
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