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Gynecologic Cancer

:	Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva
:	Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva
:	Gynecologic Cancer
:	Springer-Verlag
:	9780387287966
:	1
:	CHF 47.50
:

:	Klinische Fächer
:	English

:	312
:	Wasserzeichen/DRM
:	PC/MAC/eReader/Tablet
:	PDF

Gynecologic cancer includes cancer of the female lower genital tract: vagina, vulva, cervix, endometrium, uterus, and ovaries.

Gynecologic Cancer is the fourth volume in the M.D. Anderson Cancer Care Series, featuring the current standard approach to gynecologic cancer care from the experts at M.D. Anderson Cancer Center.

Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include primary prevention and early detection, preinvasive diseases of female lower genital tract, pathology and imaging of gynecologica malignancies, treatment of vaginal, cervical, endometrial, uterine cancers. Discussions also address fertility-sparing options for treatment of women with gynecologica cancers as well as sexuality in women with gyn malignancies. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as 'key practice points' highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with gynecologic cancer.

	CONTENTS	12
	FOREWORD --- Maurie Markman,	8
	PREFACE	9
	CONTRIBUTORS	14
	1 MULTIDISCIPLINARY CARE OF PATIENTS WITH GYNECOLOGIC CANCER S --- David M. Gershenson, John J. Kavanagh, Patricia J. Eifel, and Elvio G. Silva	17
	Chapter Overview	17
	Introduction	17
	Organization of Multidisciplinary Clinical Trial Research	18
	Gynecologic Oncology Multidisciplinary Planning Conference	19
	Gynecologic Oncology Multidisciplinary Planning Clinic	19
	Gynecologic Cancer Practice Guidelines	20
	2 PREVENTION AND EARLY DETECTION OF ENDOMETRIAL AND OVARIAN CANCERS --- Karen H. Lu	28
	Chapter Overview	28
	Introduction	29
	Endometrial Cancer	29
	Prevention for Women at Average Risk	29
	Prevention and Screening for Women with Lynch Syndrome	29
	Prevention and Screening for Women Taking Tamoxifen	30
	Prevention and Screening for Obese Women	31
	Ovarian Cancer	31
	Prevention and Screening for Women with Hereditary Breast-Ovarian Cancer Syndrome	32
	Summary	34
	3 PREINVASIVE DISEASE OF THE LOWER GENITAL TRACT --- Andrea Milbourne and Michele Follen	36
	Chapter Overview	36
	INTRODUCTION	37
	EVALUATION OF PATIENTS WITH AN ABNORMAL PAP TEST RESULT	37
	EVALUATION OF SPECIAL CASES	40
	CONCLUSION	43
	4 SELECTED TOPICS IN GYNECOLOGIC PATHOLOGY --- Anais Malpica, Michael T. Deavers, and Elvio G. Silva	46
	Chapter Overview	46
	Vulvar Intraepithelial Neoplasia, Simplex Type	47
	P16 IN CERVICAL INTRAEPITHELIAL NEOPLASIA	48
	LARGE CELL NEUROENDOCRINE CARCINOMA OF THE CERVIX	49
	Endocervical Adenocarcinoma Versus Endometrial Adenocarcinoma	51
	ENDOMETRIAL HYPERPLASIA AND CARCINOMA	53
	DEDIFFERENTIATED ENDOMETRIOID ADENOCARCINOMA	54
	GRADING OF OVARIAN SEROUS CARCINOMA	56
	INVASIVE IMPLANTS OF OVARIAN SEROUS BORDERLINE TUMORS	57
	MUCINOUS TUMORS OF THE OVARY	58
	CELLULAR FIBROMA OF THE OVARY	60
	5 IMAGING OF GYNECOLOGIC MALIGNANCIES --- Revathy Iyer	65
	Chapter Overview	65
	Introduction	66
	Imaging Modalities	67
	Cervical Cancer	69
	Endometrial Cancer	71
	Ovarian Cancer	73
	Lymphadenopathy	76
	Suggested Readings	77
	6 CONTEMPORARY TREATMENT OF VAGINAL AND VULVAR CANCERS --- Patricia J. Eifel and Thomas W. Burke	80
	Chapter Overview	80
	Introduction	81
	Epidemiology	82
	Anatomy and Patterns of Spread	82
	Clinical Evaluation and Staging	84
	Prognostic Factors	85
	Treatment of Vaginal Carcinomas	87
	Treatment of Vulvar Carcinomas	93
	Suggested Readings	100
	7 TREATMENT OF EARLY CERVICAL CANCER --- Charles F. Levenback	103
	Chapter Overview	103
	Introduction	104
	Clinical Presentation	104
	History and Physical Examination	105
	Staging	105
	Impact of Histologic Subtype on Treatment Planning	108
	Treatment Recommendations for Microinvasive Cervical Cancer	109
	Treatment Recommendations for Stage IB1 Disease: Surgery Versus Radiotherapy	110
	Treatment Recommendations for Stage IB2 Disease	113
	Radical Hysterectomy for Early Cervical Cancer	113
	Suggested Readings	116
	8 TREATMENT OF LOCALLY ADVANCED CERVICAL CANCER --- Anuja Jhingran, Patricia J. Eifel, and Pedro T. Ramirez	118
	Chapter Overview	118
	Introduction	119
	Clinical Evaluation	119
	General Treatment Approach	120
	Radiation Therapy Technique	124
	Para-aortic Radiation Therapy	131
	Treatment of Stage IVA Disease	134
	Treatment of Locally Recurrent Disease	134
	Treatment of Stage IVB Disease at Presentation or Recurrence	136
	Complications of Radiation Therapy	137
	Suggested Readings	139
	9 UTERINE SARCOMAS --- Lois M. Ramondetta, Diane C. Bodurka, Michael T. Deavers, and Anuja Jhingran	141
	Chapter Overview	142
	Introduction	142
	Uterine Malignant Mixed Müllerian Tumors	143
	Epidemiology and Tumor Features	143
	Surgical Treatment	144
	Pathologic Evaluation	145
	Radiation Therapy	146
	Chemotherapy	147
	Hormonal Therapy	148
	Treatment Summary	148
	Leiomyosarcoma	148
	Endometrial Stromal Sarcoma	153
	Undifferentiated Sarcomas	157
	Adenosarcoma	157
	Summary	159
	Suggested Readings	160
	10 TREATMENT OFENDOMETRIAL CANCER --- Lois M. Ramondetta, Thomas W. Burke, Russell Broaddus, and Anuja Jhingran	164
	Chapter Overview	164
	Introduction	165
	Epidemiology	165
	Pretreatment Evaluation	166
	Surgical Treatment	168
	Surgical Staging	169
	Tumor Features	170
	Pathologic Evaluation of the Hysterectomy Specimen	172
	Adjuvant Treatme	173
	Treatment of Residual Disease	177
	Treatment of Recurrent Disease	182
	Hormone Replacement Therapy	185
	Suggested Readings	186
	11 SURGERY FOR OVARIANCANCER --- Judith K. Wolf and J. Taylor Wharton	191
	Chapter Overview	191
	Introduction	192
	Exploratory Laparotomy and Primary Tumor Debulking	192
	Interval Debulking Surgery	197
	Second-Look Surgery	198
	Secondary Tumor Debulking	199
	Surgery for Palliation	200
	Summary	202
	Suggested Readings	202
	12 CHEMOTHERAPY FOR EPITHELIAL OVARIAN CANCER --- Michele L. Donato, Xipeng Wang, John J. Kavanagh, and David M. Gershenson	204
	Chapter Overview	204