This book, in conjunction with the volume LNAI 5288, constitutes the refereed proceedings of theFirst World Summit, WSKS 2008, held in Athens, Greece, in September 2008. The 95 revised full papers presented were carefully reviewed and selected from 286 submissions. The topics include applications for the human and the society, information systems and information technology, knowledge management and e-learning, libraries, digital culture and electronic tourism, e-business, egovernment and e-banking, politics and policies for the knowledge society, sustainable development for the knowledge society.