Fast Facts: Comprehensive Genomic Profiling Making precision medicine possible
:
B.L. Rapoport, G. Troncone, F. Schmitt, S. Nayler
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Fast Facts: Comprehensive Genomic Profiling Making precision medicine possible
:
Karger
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9783318068191
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1
:
CHF 0.50
:
:
Nichtklinische Fächer
:
English
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108
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DRM
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PC/MAC/eReader/Tablet
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ePUB/PDF
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents:• Genetic mutations and biomarkers• Understanding next-generation sequencing• Elements of comprehensive genomic profiles• Role in precision oncology• Predictive and prognostic biomarkers• Overcoming barriers to genotype-directed therapy