Dieses englischsprachige Buch ist ein Standardwerk zur Gastroenterologie bei Kleintieren. Das Autorenteam vonüber 30 international renommierten Spezialisten aus Europa und den USA liefert den State of the Art dieser Fachdisziplin und stellt den derzeitigen Standard in Diagnostik und Therapie gastrointestinaler Erkrankungen vor. Der erste Abschnitt des Buches zeigt das breite Spektrum der diagnostischen Möglichkeiten bei Erkrankungen des Magen-Darm-Traktes.

Dabei steht der problemorientierte Ansatz im Mittelpunkt. Ausführliche Kapitel beschreiben bewährte Diagnostik bei typischen Symptomkomplexen wie der akuten Magen-Darm-Problematik, chronischem Erbrechen, chronischem Durchfall und Gewichtsverlust. Im zweiten Abschnitt fokussieren die Autoren spezifische Erkrankungen der einzelnen Abschnitte des Magen-Darm-Traktes. Krankheiten, die mehrere Organe betreffen, werden in einem eigenen Kapitel betrachtet. Die einzelnen Kapitel beginnen mit einer kurzen Einführung in die Anatomie und P hysiologie des Organs. Dann konzentrieren sie sich detailliert auf die klinischen Aspekte der verschiedenen Erkrankungen.

Synopsis
Great advances have been made recently in small animal gastroenterology. This book has been written by authors from around the world with a variety of backgrounds using evidence-based medicine. The book has two main sections and the first covers the diagnosis of gastrointestinal disorders. This section contains chapters on various different diagnostic methods and on the most commonly observed clinical signs of gastrointestinal disease presented in dogs and cats, acute gastrointestinal signs, chronic vomiting, chronic diarrhea, and weight loss. The second section of the book focuses on specific diseases of the gastrointestinal tract. Each component of the GI tract is discussed separately with another section focusing on diseases that affect more than one organ of the gastrointestinal tract. The book is well referenced and fully illustrated throughout. It is concise but detailed enough for both veterinarians in training and in practice.

2 Clinical Evaluation of Dogs and Cats with Specific Clinical Signs (p. 115)

2.1 Clinical Evaluation of Patients with Acute Signs of Gastrointestinal Disease

Keith P. Richter

2.1.1 Introduction
Acute gastrointestinal disease is a common reason for dogs and cats to be presented for veterinary care. Clinical signs can range from mild and self-limiting to severe and life-threatening. These signs can be divided into regurgitation, vomiting, diarrhea, or any combination there of. The initial clinical evaluation must take into account the severity of the animal’s condition. This will help determine the extent of the diagnostic evaluation and guide initial treatment strategies. In cases with mild clinical signs, the diagnostic evaluation may be limited, and require only outpatient symptomatic care. In animals with severe clinical signs, a more thorough evaluation and inpatient care may be necessary. Complications of vomiting and diarrhea include dehydration, electrolyte imbalances, acid-base disturbances, aspiration pneumonia, and malnutrition and /or protein depletion. In most cases, it is helpful to establish a definitive diagnosis, but this is not always necessary or possible.

2.1.2 Diagnostic evaluation of vomiting

2.1.2.1 Vomiting versus regurgitation

It is critical to distinguish between vomiting, regurgitation, and gastroesophageal reflux when obtaining the initial history, because the diagnostic and treatment approaches are vastly different. Vomiting is a reflex act that includes prodromal signs followed by active abdominal contractions. The prodromal signs may include behavioral changes, salivation, and repeated swallowing attempts. It must be emphasized that these signs are variable. In contrast, regurgitation is a passive act that is often spontaneous or associated with changes in body position. There are no prodromal signs and there are no repetitive abdominal contractions. Regurgitation is typically associated with disorders of the esophagus (see 3.3). The best way to differentiate these two clinical signs is to imitate the two acts for the client, emphasizing the repetitive abdominal contractions seen in the vomiting patient as the most reliable distinguishing feature. The timing of the event with respect to eating, the volume of material brought up, or the character of the contents (unless it contains bile, suggestive of vomiting) do not reliably distinguish vomiting from regurgitation.

2.1.2.2 The vomiting reflex

The vomiting reflex begins with afferent receptors located in visceral organs (including GI tract, pancreas, heart, liver, genitourinary tract, and peritoneum) and the pharynx.1 The afferent impulses travel through the vagus and sympathetic nerves to the vomiting center located in the medulla. Vomiting can also be initiated by stimulation of the chemoreceptor trigger zone (CRTZ) located in the area postrema of the medulla.1 The CRTZ is sensitive to blood-borne substances. The vomiting reflex can also be initiated by input from the cerebral cortex (rare in animals vs. human beings) and from the vestibular apparatus (i. e., motion sickness). Thus, vomiting can be initiated through a"humoral" pathway, caused by blood-borne substances stimulating the CRTZ, or a"neural" pathway, caused by stimulation of the vomiting center from vagosympathetic, CRTZ, vestibular, or cerebral neurons.