: André Jaggy, Platt, Simon
: Atlas and Textbook of small animal neurology An Illustrated Text
: Schlütersche
: 9783899930924
: 1
: CHF 150.40
:
: Veterinärmedizin
: English
: 611
: DRM
: PC/MAC/eReader/Tablet
: PDF
Die englische Übersetzung der deutschen Ausgabe des Buches wurde für den englischsprachigen Markt überarbeitet. Das Buch liefert eine umfassende Zusammenstellung der Kleintierneurologie in allen klinischen Fragestellungen. Der allgemeine Teil präsentiert detaillierte Ausführungen zum neurologischen Untersuchungs-gang, zur Neuropathologie und zu genetischen Krankheiten. Einen guten Einstieg in die praxisrelevanten Grundlagen der Neurologie geben einzelne Kapitel zu Laboruntersuchungen, Anästhesie, Radiologie und Elektrodiagnostik, Rehabilitation, Pharmakologie. Die Neurochirurgie und neurologische Notfälle werden ausführlich vorgestellt. Der spezielle Teil geht auf die spezifischen neurologischen Erkrankungen nach ihrer Lokalisation ein und bietet konkrete Angaben zur Diagnose und Therapie besonderer Krankheitsbilder. Außergewöhnlich sind die Darstellung der Neuroanatomie und -pathologie mit Bildgebenden Verfahren als Bildanhang im Buch und die beigelegte CD-ROM mit der Darstellung des Untersuchungsganges und neurologischen Fallbeispielen.
20 Parasitic Neurological
Diseases of the Dog and Cat , (S. 491-492)


Peter Deplazes


Various helminth and protozoal species are capable of infesting nervous tissue either transiently or permanently. The following overview includes information about a selection of clinically relevant parasites that affect the nervous tissues directly or indirectly via pathophysiological or immunopathological mechanisms.

20.1 Trypanosomiasis in the dog

General information and epidemiology: Trypanosomiasis of the dog is a rare imported disease. Trypanosomes in tropical Africa (Trypanosoma brucei and T. congolense) are transmitted by the tsetse fly, while in the subtropical areas of Africa, Asia and South America, T. evansi is transmitted by tabanid flies and Stomoxys spp. Dogs can also become infected by T. evansi by ingesting meat from infected herbivores. Another trypanosome species present in South and Central America is T. cruzi, which is transmitted by ticks, and is found in up to 30% of dogs and 20% of cats (Chaga’s disease).

However, as stated at the start, imported trypanosome infections are very rare. Clinical: Trypanosomiasis can be acute or chronic in the dog. In the acute form, the main symptoms are a febrile, rapidly deteriorating systemic disease causing a loss of condition, anaemia, leukopaenia, thrombocytopaenia, circulatory and respiratory symptoms, multiple generalised haemorrhages and oedema, conjunctivitis and corneal clouding (1, 2). Except for T. congolense, CNS symptoms can occur due to a meningoencephalomyelitis associated with the presence of extravascular trypanosomes (3). In such cases, death takes only a few days. Neurological signs may also occur as part of a chronic clinical picture and are determined by the location of the parasitic migration.

Diagnosis: The extracellular trypanosomes in the blood can be diagnosed by staining them in blood smears with Giemsa. Therapy: Treatment can be tried with quinapyramine sulphate (5 mg/kg, SC) or isomethamidium (0.25–1 mg/kg, IM). Both medications, however, are associated with severe side-effects (4).

20.2 Neosporosis in the dog

General information:The taxonomic position of Toxoplasma gondii and Hammondia heydorni are very close, while that of Neospora caninum, a species described in 1984, remains controversial (4, 5). Infection with N. caninum is increasingly associated with paralysis and death in the dog, as well as abortion and neonatal deaths in cattle and small ruminants.

The latest data convincingly demonstrate that N. caninum is one of the most important causes of abortion in cattle in Europe and is widely geographically distributed (6). Infections with Neospora have not as yet been reported in humans. Epidemiology: Using experimental infections, it has been shown that the dog can be a final host of N. caninum. In addition, naturally infected dogs have been shown to excrete Neospora oocytes (8). In comparison, the fox does not appear to be a suitable final host (9).
Table of Contents8
Contributors17
Preface to the English edition22
Preface to the second German edition23
Preface to the first German edition24
Abbreviations25
1 Neurological Examination of Small Animals28
1.1 Signalment28
1.2 Anamnesis28
1.3 General examination29
1.4 Neurological status29
1.5 Ophthalmological examination61
Literature64
2 Principles of Neuropathology66
2.1 General neuropathology66
2.2 Classification of neurological diseases: VITAMIN D75
2.3 Investigation of the cerebrospinal fluid ( CSF)80
Further reading82
3 Genetic Neurological Diseases and Breed Predisposition84
3.1 Genetic defects84
3.2 Inheritance85
3.3 Demonstrating the mode of inheritance85
3.4 Testing for potential genetic carriers87
3.5 Breeding methods to eradicate genetic defects88
3.6 Diseases due to multifactorial causes89
Literature90
4 Basic Laboratory Investigations92
4.1 Indications92
4.2 Haematology93
4.3 Biochemical blood parameters95
4.4 Urine investigations98
Further reading98
5 Anaesthesia100
5.1 Basics of neuroanaesthesia100
5.1.1 Control of intracranial pressure101
5.1.2 Control of the carbon dioxide partial pressure102
5.1.3 Control of blood pressure103
5.1.4 Pharmaceuticals103
5.1.5 Positioning104
5.1.6 Supervision of anaesthesia and hypothermia104
5.1.7 Fluid therapy104
5.1.8 Recovery period105
5.2 Specific procedural techniques105
Literature112
Further reading112
6 Neuroradiology114
6.1 Indications114
6.2 Examination methods116
6.3 Spine124
6.4 Specific diseases139
6.5 Skull152
Literature172
7 Electrodiagnostics180
7.1 Electrodiagnosis of the peripheral nervous system ( PNS)181
7.1.1 Electromyography (EMG)182
7.1.2 Electroneurography184
7.1.3 Auditory evoked potentials (AEP)188
7.2 Electrodiagnostic examinations of the CNS 7.2.1 Electroencephalography190
7.3 Biopsy196
7.3.1 Muscle biopsy196
7.3.2 Nerve biopsy197
8 Rehabilitation198
8.1 Physiotherapy198
8.1.1 Hydrotherapy199
8.1.2 Massage199
8.1.3 Kinesiotherapy201
8.1.4 Electrotherapy202
8.1.5 Thermotherapy205
8.1.6 Magnetic field therapy205
8.2 Adjuvant therapeutic measures205
9 Neuropharmacology210
9.1 Antibiotic therapy in neurological disease210
9.1.1 Classes of antibiotics and their antibiotic spectra210
9.1.2 Choice of antibiotic depending on neurological lesion localisation213
9.2 Steroid therapy214
9.2.1 Chemistry, pharmacokinetics and clinical pharmacology214
9.2.2 Physiological and pharmacological effects215
9.2.3 Side-effects216
9.2.4 Therapeutic uses216
9.3 Analgesics218
9.3.1 Principles of pain physiology and therapy219
9.3.2 Opioids220
9.3.3 Non-steroidal anti-inflammatory drugs220
9.3.4 Other medications and treatments used in pain relief223
Literature224
Further reading224
10 Neurosurgery226
10.1 Instrumentation226
10.2 Brain227
10.2.1 Brain tumours228
10.2.2 Cranial trauma231
10.2.3 Hydrocephalus232
10.3 Spinal cord/ Spine233
10.3.1 Diseases of the intervertebral discs233
10.3.2 Diseases of the cervical intervertebral discs234
10.3.3 Diseases of the thoracolumbar intervertebral discs237
10.3.4 Diseases of the lumbosacral intervertebral discs239
10.3.5 Tumours of the vertebral body, spinal cord and nerve roots239
10.4 Spinal fractures / luxations242
10.5 Peripheral nerves249
10.6 Surgery of the middle and inner ear254
11 Acupuncture258
11.1 Introduction258
11.1.1 Acupuncture in traditional Chinese medicine ( TCM)258
11.1.2 The acupoints258
11.1.3 Choice of acupoints259
11.1.4 Activation of the acupoints259
11.2 The use of acupuncture in neurological disease260
11.3 Acupunctural analgesia and postoperative pain relief261
12 Stabilization of the Neurological Emergency Patient264