: J.L. Meyer
: IMRT, IGRT, SBRT Advances in the Treatment Planning and Delivery of Radiotherapy.
: Karger
: 9783805596817
: 1
: CHF 213.40
:
: Klinische Fächer
: English
: 506
: DRM
: PC/MAC/eReader/Tablet
: PDF/ePUB
Over the last 4 years, IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy has become a standard reference in the field. During this time, however, significant progress in high-precision technologies for the planning and delivery of radiotherapy in cancer treatment has called for a second edition to include these new developments. Thoroughly updated and extended, this new edition offers a comprehensive guide and overview of these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity-modulated radiotherapy (IMRT), and 4D and adaptive treatment planning are clearly presented. Target localization and image-guided radiotherapy (IGRT) systems are comprehensively reviewed as well. Clinical tutorials illustrate target definitions for the major cancer sites, and useful techniques for organ motion management are described and compared. There are also several chapters that explore the technical basis and latest clinical experience with stereotactic body radiotherapy (SBRT) and summarize practical treatment recommendations. Furthermore, the significant and increasing contributions of proton therapy to cancer care are also highlighted, alongside the practical allocation of all these new technologies from an economic perspective. As a highlight of this volume, a number of images can be viewed online in time-elapse videos for greater clarity and more dynamic visualizationWritten by leading authorities in the field, this comprehensive volume brings clinical and technical practitioners of radiotherapy fully up to date with the key developments in equipment, technologies and treatment guidelines.
Cover1
Contents6
Preface10
Introduction12
Advances in the Planning and Delivery of Radiotherapy: New Expectations, New Standards of Care12
Abstract12
The Expansion of Radiation Oncology Technologies12
Target Volume Specification and Treatment: Issues of Accuracy16
Intensity-Modulated Radiation Therapy/Image-Guided Radiation Therapy Planning and Delivery Technologies: Current Challenges19
Proton and Heavy Ion Radiation Therapy30
Radiation Dose and Second Cancers32
Radiation Oncology Informatics34
Conclusions35
References37
General Concepts and Methods40
Advanced Technologies in the Radiotherapy Clinic: System Fundamentals40
Abstract40
A Typical Intensity-Modulated Radiotherapy Treatment Planning System41
Target Localization and Image Guidance43
Image Registration52
Adaptive Radiotherapy61
References66
Economic Perspectives71
Controversies in the Adoption of New Healthcare Technologies71
Abstract71
Health Technology Assessment71
Payment Policy Development: Past and Present Realities, and Future Uncertainties77
Cost-Effectiveness Methodologies, Implications in an Era of Value-Based Purchasing83
Conclusions88
References89
IMRT: Advances in Treatment Design and Delivery91
Clinical Implementation of Intensity-Modulated Arc Therapy91
Abstract91
Intensity-Modulated Arc Therapy: Basic Concepts92
Why Rotational Intensity-Modulated Radiation Therapy?93
Commercial Intensity-Modulated Arc Therapy Solutions96
Clinical Implementation of Intensity-Modulated Arc Therapy99
References108
IGRT: Advances in Targeting Therapy110
4D Imaging and 4D Radiation Therapy: A New Era of Therapy Design and Delivery110
Abstract110
Impact of Breathing Motion on Images111
Impact of Breathing Motion during Treatments117
Methods to Account for Breathing Motion120
Future Directions126
Acknowledgements127
References127
Locating and Targeting Moving Tumors with Radiation Beams129
Abstract129
How Do We Locate the Moving Target?133
How Do We Hit a Moving Target?137
How Do We Create Integrated Systems to Locate and Hit Moving Targets?139
Conclusions139
References140
Integrating IMRT and IGRT into Treatment Delivery143
Technologies of Image Guidance and the Development of Advanced Linear Accelerator Systems for Radiotherapy143
Abstract143
Technologies to Meet the Goals of Image-Guided Radiation Therapy146
Image Guidance Systems and Procedures148
Cone-Beam CT for Linac-Based Image-Guided Radiation Therapy154
Image Guidance: Meeting Future Needs165
Conclusions169
References169
HelicalTomotherapy: Image-Guided and Adaptive Radiotherapy176
Abstract176
System Overview177
Clinical Applications of Helical Tomotherapy178
Daily Megavoltage-Based CT Imaging179
Dose Evaluation and Adaptive Radiotherapy186
Conclusions190
References190
The CyberKnife in Clinical Use: Current Roles, Future Expectations192
Abstract192
The CyberKnife System192
Advances in CyberKnife Treatment Planning and Dose Delivery194
Current Clinical Applications of CyberKnife199
The Future of CyberKnife202
References203
Image Guidance and the New Practice of Radiotherapy: What to Know and Use from a Decade of Investigation207
Abstract207
The Rationale for Image-Guided Radiation Therapy: Perspectives on the Current Practice of Radiotherapy207
Challenges in Image-Guided Radiation Therapy213
Clinical Applications of Image-Guided Radiation Therapy217
Adaptive Radiotherapy223
Conclusions225
References226
Head and Neck Cancers228
Intensity-Modulated and Image-Guided Radiation Therapy for Head and Neck Cancers228
Abstract228
Intensity-Modulated Radiation Therapy/Image-Guided Radiation Therapy Planning for Head and Neck Cancers229
Intensity-Modulated Radiation Therapy for Nasopharyngeal Carcinomas245
Intensity-Modulated Radiation Therapy for Oropharyngeal Carcinomas256
Conclusions260
Guidelines for Clinical Practice261
References262
Delineating Neck Targets for Intensity-Modulated Radiation Therapy of Head and Neck Cancer266
Abstract266
Tumor and Target Volumes in the Neck267
Target Doses and Techniques275
Case Studies278
Guidelines for Clinical Practice278
References280